To get through level 161 you need to clear all of the jelly and score 55,000 points in 45 moves. The locked in pieces are an obstacle but the real difficulty in the level comes from the three chocolate fans. Both the locked in pieces and the expanding chocolate reduce the space you have to work with making it harder to get bigger matches. The chocolate poses the bigger problem of the two, though, because it covers the jelly pieces. You can quickly lose track of
which jellies you have cleared and which you have not when they are covered with chocolate. And they get covered quickly because the jellies are doubles. A tip is to take a screenshot of the grid as soon as you start the level. Then pause the game each time you clear a jelly and mark it off on your screenshot.